How are the best healthcare startups ranked?

Startups are ranked by commit velocity change, the percentage change in 14-day commit counts versus the previous period. This measures engineering acceleration, which has historically preceded fundraise announcements by three to six weeks. Data sourced from public GitHub activity.

2026 Rankings

Best Healthcare Startups 2026

Q: What are the best healthcare startups in 2026?

The best healthcare startups in 2026, ranked by engineering acceleration: 1. aphp (+999% commit velocity change), 2. StanfordSpezi (+999% commit velocity change), 3. ere-health (+999% commit velocity change), 4. epic-open-source (+999% commit velocity change), 5. insightsengineering (+999% commit velocity change). Rankings based on public GitHub engineering activity data from VC Deal Flow Signal.

Direct answer

The top healthcare startups in 2026, ranked by GitHub engineering acceleration. These are the companies whose engineering teams are shipping the fastest, a signal that has historically preceded fundraise announcements by three to six weeks.

Key Takeaway

In Q3 2026, 8 of 26 tracked healthcare startups show positive engineering acceleration. aphp leads with 1 commits over 14 days (+999% change). The dominant signal pattern is "Deceleration". Average sector commit velocity is 53 commits per 14-day window. These engineering momentum signals have historically preceded fundraise announcements by three to six weeks.

#	Company	Stage	Geo	Commits (14d)	Change	Contributors	Contrib. Growth	New Repos	Signal
1	aphp aphp is ahealthcare pre-seed startup based in EU, investing in platform infrastructure and new product lines. View signal profile →	Pre-seed	EU	1	+999%	3	+0%	3	Infrastructure buildout
2	StanfordSpezi Free and open-source ecosystem of modules enabling digital health systems View signal profile →	Pre-seed	US	5	+999%	5	+0%	0	Deploy frequency spike
3	ere-health der virtuelle E-Rezept Drucker View signal profile →	Series A/B	EU	1	+999%	30	+0%	0	Deploy frequency spike
4	epic-open-source Epic develops software to help people get well, help people stay well, and help future generations be healthier. View signal profile →	Seed	Unknown	2	+999%	18	+300%	0	Engineering hiring burst
5	insightsengineering Roche/Genentech - Insights Engineering View signal profile →	Seed	EU	2	+999%	9	+0%	2	Deploy frequency spike
6	tuva-health The community building the future of healthcare analytics View signal profile →	Series A/B	US	3	+999%	48	+0%	3	Infrastructure buildout
7	neuml NeuML is the company behind txtai, one of the most popular open-source AI frameworks in the world. View signal profile →	Series A/B	Unknown	25	+400%	26	+0%	0	Deploy frequency spike
8	third-culture-software third culture software is ahealthcare series a/b startup, modernizing their technology stack for scale. View signal profile →	Series A/B	Unknown	25	+19%	28	+34%	0	Framework migration
9	pharmaverse pharmaverse is ahealthcare growth startup based in EU, modernizing their technology stack for scale. View signal profile →	Growth	EU	2	+0%	97	+0%	0	Framework migration
10	simpledotorg The fast, free app for clinicians to track patients with high blood pressure and diabetes. View signal profile →	Series A/B	Unknown	1	+0%	37	+0%	1	Framework migration
11	zapplyjobs Free job boards and career resources for students & new grads View signal profile →	Pre-seed	US	992	-27%	7	+0%	2	Deceleration
12	healthchainai Building developer tools and for the next generation of healthcare AI applications. View signal profile →	Seed	UK	8	-27%	14	+180%	1	Deceleration
13	hpi-studyu hpi studyu is ahealthcare seed startup based in EU, rapidly expanding their engineering team. View signal profile →	Seed	EU	35	-33%	17	+74%	0	Deceleration
14	HeliosSoftware Enterprise healthcare software providing practice management and electronic health record solutions. View signal profile →	Seed	US	62	-40%	14	+0%	0	Deceleration
15	sunlabuiuc sunlabuiuc is ahealthcare growth startup, modernizing their technology stack for scale. View signal profile →	Growth	Unknown	1	-50%	56	+0%	0	Deceleration
16	medplum Healthcare infrastructure View signal profile →	Growth	US	44	-56%	185	+0%	2	Deceleration
17	samply samply is ahealthcare series a/b startup, rapidly expanding their engineering team. View signal profile →	Series A/B	Unknown	21	-58%	20	+59%	0	Deceleration
18	HasteHealth Digital health platform streamlining clinical documentation and patient engagement for healthcare providers. View signal profile →	Pre-seed	Unknown	23	-60%	6	+0%	0	Deceleration
19	ohcnetwork Opensource Public Utility \| Open Healthcare Network View signal profile →	Growth	APAC	11	-61%	330	+0%	6	Deceleration
20	FreedomIntelligence Healthcare AI platform enabling secure federated learning and privacy-preserving medical data collaboration. View signal profile →	Seed	Unknown	35	-62%	16	+52%	4	Deceleration
21	earthians earthians Health Informatics Pvt. Ltd. View signal profile →	Growth	APAC	18	-62%	86	+129%	0	Deceleration
22	the-momentum Building scalable, secure, and compliant healthtech solutions. We empower startups and scaleups to innovate and grow and View signal profile →	Seed	Unknown	3	-73%	9	+400%	0	Deceleration
23	fedbiomed Collaborative learning in heathcare View signal profile →	Series A/B	Unknown	4	-73%	23	+4%	0	Deceleration
24	HCW-home Simple & Secure remote consultations View signal profile →	Pre-seed	EU	4	-83%	4	+0%	0	Deceleration
25	masslight masslight is ahealthcare series a/b startup, modernizing their technology stack for scale. View signal profile →	Series A/B	Unknown	53	-83%	28	+0%	0	Deceleration
26	hapifhir This is the source home for the HAPI FHIR project. Note that we are in the progress of migrating our codebase from the m View signal profile →	Growth	Unknown	4	-85%	267	+0%	0	Deceleration

Ranked by commit velocity change (14-day window). Data: Q3 2026.

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Frequently Asked Questions

What are the best healthcare startups in 2026?

Based on GitHub engineering acceleration data, the top healthcare startups in 2026 are aphp, StanfordSpezi, ere-health, epic-open-source, insightsengineering. Rankings are based on commit velocity change, the rate at which engineering output is accelerating.

How are these rankings determined?

Startups are ranked by commit velocity change, the percentage change in 14-day commit counts versus the prior period. This measures engineering acceleration, not absolute size. Read the full methodology.

View detailed Healthcare rankings for Q3 2026→

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